CXCL14 Protein
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- Target See all CXCL14 Proteins
- CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human CXCL14 / BRAK protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Biological Activity Comment
- ED50 is 1.0-10.0 ng/ml as determined by the ability of Recombinant CXCL14 to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells.
- Top Product
- Discover our top product CXCL14 Protein
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Chemokine (C-X-C Motif) Ligand 14 (CXCL14) (Active) protein
CXCL14 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Chemokine (C-X-C Motif) Ligand 14 (CXCL14) (AA 23-99) protein (His tag)CXCL14 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-X-C Motif) Ligand 14 (CXCL14) (AA 35-111) protein (His-IF2DI Tag)CXCL14 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chemokine (C-X-C Motif) Ligand 14 (CXCL14) (AA 1-111) protein (GST tag)CXCL14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 1M NaCl, pH 8.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))
- Alternative Name
- Cxcl14,brak (CXCL14 Products)
- Synonyms
- BMAC Protein, BRAK Protein, KEC Protein, KS1 Protein, MIP-2g Protein, MIP2G Protein, NJAC Protein, SCYB14 Protein, 1110031L23Rik Protein, 1200006I23Rik Protein, AI414372 Protein, Kec Protein, MIP2gamma Protein, Scyb14 Protein, bolekine Protein, scyba Protein, fb67g04 Protein, wu:fb67g04 Protein, JSC Protein, bmac Protein, brak Protein, kec Protein, ks1 Protein, mip-2g Protein, mip2g Protein, njac Protein, scyb14 Protein, CXCL14 Protein, DKFZp469J175 Protein, C-X-C motif chemokine ligand 14 Protein, chemokine (C-X-C motif) ligand 14 Protein, chemokine (C-X-C motif) ligand 14 L homeolog Protein, CXCL14 Protein, Cxcl14 Protein, cxcl14 Protein, cxcl14.L Protein
- Background
- This antimicrobial gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation.
- Molecular Weight
- 9.4 kDa
- NCBI Accession
- NP_004878
- Pathways
- Autophagy
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