GARP Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712908

Product Details

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This GARP protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CNGB1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: GARP (CNGB1) (Cyclic Nucleotide Gated Channel beta 1 (CNGB1))

Alternative Name: Cngb1 (CNGB1 Products)

Synonyms: CNCG2 Protein, CNCG3L Protein, CNCG4 Protein, CNG4 Protein, CNGB1B Protein, GAR1 Protein, GARP Protein, RCNC2 Protein, RCNCb Protein, RCNCbeta Protein, RP45 Protein, Gm1959 Protein, Cngb1b Protein, CNGB1 Protein, si:ch211-160j6.1 Protein, cyclic nucleotide gated channel beta 1 Protein, cyclic nucleotide gated channel beta 1a Protein, CNGB1 Protein, Cngb1 Protein, cngb1a Protein

Background: In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 32.4 kDa

NCBI Accession: NP_001129111

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction