COASY Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2712941

Product Details

Target: COASY (CoA Synthase (COASY))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 3

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This COASY protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Coenzyme A synthase (COASY), nuclear gene encoding mitochondrial protein, transcript variant 3 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: COASY (CoA Synthase (COASY))

Alternative Name: Coenzyme A Synthase (Coasy) (COASY Products)

Synonyms: DPCK Protein, NBP Protein, PPAT Protein, UKR1 Protein, pOV-2 Protein, 1300003G02Rik Protein, Dpck Protein, Ppat Protein, Ukr1 Protein, COASY Protein, zgc:92337 Protein, PPAT/DPCK Protein, Coenzyme A synthase Protein, CoA synthase Protein, bifunctional coenzyme A synthase Protein, Bifunctional coenzyme A synthase Protein, COASY Protein, Coasy Protein, CpipJ_CPIJ008826 Protein, pco122135 Protein, coasy Protein

Background: Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.

Molecular Weight: 62.1 kDa

NCBI Accession: NP_001035995

Pathways: Ribonucleoside Biosynthetic Process