RCAN1 Protein (His tag)

Catalog No. ABIN2713038

Product Details

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RCAN1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Calcipressin-1 (full length, N-term HIS tag, transcript variant 3) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 50 mM Tris, 8M Urea, pH 8.0.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: Calcipressin-1 (RCAN1 Products)

Synonyms: ADAPT78 Protein, CSP1 Protein, DSC1 Protein, DSCR1 Protein, MCIP1 Protein, RCN1 Protein, RCAN1 Protein, 2410048A02Rik Protein, AA408855 Protein, AI429645 Protein, AL024459 Protein, AV028423 Protein, Adapt78 Protein, CALP1L Protein, Dscr1 Protein, Mcip1 Protein, dscr1 Protein, rcan1 Protein, wu:fr92c05 Protein, adapt78 Protein, csp1 Protein, dsc1 Protein, mcip1 Protein, MGC53636 Protein, rcn1 Protein, MGC69428 Protein, regulator of calcineurin 1 Protein, regulator of calcineurin 1b Protein, regulator of calcineurin 1 L homeolog Protein, Down syndrome critical region gene 1 Protein, RCAN1 Protein, Rcan1 Protein, rcan1b Protein, rcan1.L Protein, dscr1 Protein, rcan1 Protein

Background: The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.

Molecular Weight: 22.6 kDa

NCBI Accession: NP_981963

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development