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CASQ2 Protein (Myc-DYKDDDDK Tag)

CASQ2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713078
  • Target See all CASQ2 Proteins
    CASQ2 (Calsequestrin 2 (CASQ2))
    Protein Type
    Recombinant
    Origin
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This CASQ2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Calsequestrin-2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CASQ2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CASQ2 (Calsequestrin 2 (CASQ2))
    Alternative Name
    Calsequestrin-2 (CASQ2 Products)
    Synonyms
    CASQ2 Protein, DKFZp468D075 Protein, AA033488 Protein, AW146219 Protein, ESTM52 Protein, cCSQ Protein, PDIB2 Protein, cardCSQ Protein, CASQ1 Protein, CAL Protein, calsequestrin 2 Protein, CASQ2 Protein, Casq2 Protein
    Background
    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
    Molecular Weight
    44.2 kDa
    NCBI Accession
    NP_001223
    Pathways
    Negative Regulation of Transporter Activity
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