CAMKK2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713100

Product Details

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CAMKK2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CAMKK2 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))

Alternative Name: Camkk2 (CAMKK2 Products)

Synonyms: CAMKK Protein, CAMKKB Protein, 6330570N16Rik Protein, AW061083 Protein, mKIAA0787 Protein, camk2b Protein, fj90d04 Protein, wu:fj90d04 Protein, si:dkey-174n20.2 Protein, CAMKK2 Protein, calcium/calmodulin dependent protein kinase kinase 2 Protein, calcium/calmodulin-dependent protein kinase kinase 2, beta Protein, calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1 Protein, calcium/calmodulin dependent protein kinase II beta Protein, calcium/calmodulin-dependent protein kinase kinase 2 Protein, CAMKK2 Protein, Camkk2 Protein, camk2b1 Protein, CAMK2B Protein, camkk2 Protein

Background: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases.

Molecular Weight: 59.4 kDa

NCBI Accession: NP_705719

Pathways: AMPK Signaling