CBX3 Protein (His tag)

Catalog No. ABIN2713264

Product Details

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CBX3 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CBX3 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Alternative Name: Cbx3 (CBX3 Products)

Synonyms: HECH Protein, HP1-GAMMA Protein, HP1Hs-gamma Protein, Hp1-gamma Protein, HP1g Protein, M32 Protein, cbx3 Protein, cbx3a Protein, xhp1g Protein, wu:fb61b02 Protein, zgc:153397 Protein, chromobox 3 Protein, chromobox 3 L homeolog Protein, chromobox protein homolog 3 pseudogene Protein, chromobox homolog 3a (HP1 gamma homolog, Drosophila) Protein, CBX3 Protein, Cbx3 Protein, cbx3.L Protein, LOC100355282 Protein, cbx3a Protein

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011].

Molecular Weight: 20.6 kDa

NCBI Accession: NP_009207