CBX5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713266

Product Details

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CBX5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CBX5 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: Cbx5 (CBX5 Products)

Synonyms: HP1 Protein, HP1A Protein, id:ibd2026 Protein, wu:fc63e02 Protein, wu:fe47g12 Protein, wu:fi03h05 Protein, zgc:158601 Protein, CBX5 Protein, cbx5 Protein, MGC64354 Protein, 2610029O15Rik Protein, C75991 Protein, Hp1a Protein, Hp1alpha Protein, chromobox 5 Protein, chromobox homolog 5 (HP1 alpha homolog, Drosophila) Protein, chromobox 5 S homeolog Protein, CBX5 Protein, cbx5 Protein, Cbx5 Protein, cbx5.S Protein

Background: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Molecular Weight: 22 kDa

NCBI Accession: NP_001120793