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Integrin beta 4 Protein (ITGB4) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ITGB4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713356
  • Target See all Integrin beta 4 (ITGB4) Proteins
    Integrin beta 4 (ITGB4)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 5
    • 3
    Human
    Source
    • 4
    • 3
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Integrin beta 4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD104 / Integrin beta-4 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ITGB4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Integrin beta 4 (ITGB4)
    Alternative Name
    Cd104,integrin beta-4 (ITGB4 Products)
    Synonyms
    AA407042 Protein, C230078O20 Protein, CD104 Protein, integrin subunit beta 4 Protein, integrin beta 4 Protein, ITGB4 Protein, Itgb4 Protein
    Background
    Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Molecular Weight
    199.4 kDa
    NCBI Accession
    NP_000204
    Pathways
    Integrin Complex
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