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Endoglin Protein (ENG) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ENG Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713358
  • Target See all Endoglin (ENG) Proteins
    Endoglin (ENG)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 19
    • 10
    • 2
    • 2
    Human
    Source
    • 14
    • 8
    • 6
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This Endoglin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD105 / Endoglin (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ENG Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Endoglin (ENG)
    Alternative Name
    Cd105,endoglin (ENG Products)
    Synonyms
    ENG Protein, MGC137842 Protein, DKFZp469D0419 Protein, END Protein, HHT1 Protein, ORW1 Protein, AI528660 Protein, AI662476 Protein, CD105 Protein, S-endoglin Protein, endoglin Protein, ENG Protein, Eng Protein
    Background
    This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    68 kDa
    NCBI Accession
    NP_001108225
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