CD13 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713404

Product Details

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CD13 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CD13 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))

Alternative Name: CD13 (ANPEP Products)

Synonyms: APN Protein, CD13 Protein, GP150 Protein, LAP1 Protein, P150 Protein, PEPN Protein, A2AP Protein, AAP Protein, ALPHA-2-PI Protein, API Protein, PLI Protein, AAT1 Protein, ALT1 Protein, GPT1 Protein, Gpt1 Protein, Apn Protein, pepN Protein, SC8E4A.13 Protein, 1300007J06Rik Protein, 2310022B03Rik Protein, ALT Protein, Gpt-1 Protein, AP-M Protein, AP-N Protein, Cd13 Protein, Apm Protein, KZP Protein, Lap1 Protein, rAPN Protein, APDE Protein, p150 Protein, anpep Protein, fb64c05 Protein, wu:fb64c05 Protein, zgc:136771 Protein, alanyl aminopeptidase, membrane Protein, serpin family F member 2 Protein, glutamic--pyruvic transaminase Protein, aminopeptidase N Protein, aminopeptidase Protein, aminopeptidase n Protein, glutamic pyruvic transaminase, soluble Protein, alanyl (membrane) aminopeptidase Protein, membrane alanyl aminopeptidase Protein, alanyl (membrane) aminopeptidase b Protein, alanyl aminopeptidase, membrane L homeolog Protein, ANPEP Protein, SERPINF2 Protein, GPT Protein, Gpt Protein, Apn2 Protein, Apn1 Protein, SCO2643 Protein, pepN Protein, Shewana3_0897 Protein, Alvin_1024 Protein, Ndas_3413 Protein, Saut_1544 Protein, Fbal_1877 Protein, ML5_3424 Protein, Despr_1988 Protein, Mesop_5365 Protein, Anpep Protein, LOC101744250 Protein, anpepb Protein, anpep.L Protein

Background: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

Molecular Weight: 106.3 kDa

NCBI Accession: NP_001141

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones