Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD16 Protein (CD16) (Transcript Variant 1) (His tag)

CD16 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2713449
  • Target See all CD16 Proteins
    CD16
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This CD16 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human CD16 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Top Product
    Discover our top product CD16 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    CD16
    Alternative Name
    CD16 (CD16 Products)
    Synonyms
    Fcgr3 Protein, Fcgr3a Protein, CD16 Protein, FCGR3 Protein, FCGR3@ Protein, CD16b Protein, FCG3 Protein, FCR-10 Protein, FCRIII Protein, FCRIIIb Protein, FcRIII Protein, Fc fragment of IgG, low affinity IIa, receptor Protein, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) Protein, Fc fragment of IgG receptor IIIb Protein, Fc fragment of IgG receptor IIIa Protein, Fc receptor, IgG, low affinity III Protein, Fc-gamma RIII Protein, Fcgr2a Protein, FCGR3A Protein, FCGR3B Protein, Fcgr3 Protein, FCGR3 Protein
    Background
    This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    22.61kD
    NCBI Accession
    NP_000560
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
You are here:
Support