ATP1B3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713615

Product Details

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ATP1B3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CD298 / ATP1B3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ATP1B3 (ATPase, Na+/K+ Transporting, beta 3 Polypeptide (ATP1B3))

Alternative Name: Cd298,atp1b3 (ATP1B3 Products)

Synonyms: ATPB-3 Protein, CD298 Protein, AA409958 Protein, AI664000 Protein, AW212096 Protein, NKAB3S Protein, atp1b3 Protein, cb714 Protein, fb13c07 Protein, wu:fb13c07 Protein, cb713 Protein, nakatpb Protein, wu:fa14a07 Protein, ATPase Na+/K+ transporting subunit beta 3 Protein, ATPase, Na+/K+ transporting, beta 3 polypeptide Protein, ATPase Na+/K+ transporting subunit beta 3 S homeolog Protein, ATPase, Na+/K+ transporting, beta 3b polypeptide Protein, ATPase, Na+/K+ transporting, beta 3a polypeptide Protein, ATP1B3 Protein, Atp1b3 Protein, atp1b3.S Protein, atp1b3b Protein, atp1b3a Protein

Background: The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.

Molecular Weight: 31.3 kDa

NCBI Accession: NP_001670

Pathways: Thyroid Hormone Synthesis