CD44 Protein (CD44) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
(1 reference)-
- Target See all CD44 Proteins
- CD44
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CD44 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human CD44 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product CD44 Protein
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CD44 (CD44) (AA 1-699) protein (GST tag)
CD44 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
CD44 (CD44) (AA 152-311) protein (His-IF2DI Tag)CD44 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
CD44 (CD44) (AA 1-361) protein (GST tag)CD44 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
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: "A CD44 specific peptide developed by phage display for targeting gastric cancer." in: Biotechnology letters, Vol. 37, Issue 11, pp. 2311-20, (2015) (PubMed).
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- Target
- CD44
- Alternative Name
- CD44 (CD44 Products)
- Background
- The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
- Molecular Weight
- 79.2 kDa
- NCBI Accession
- NP_000601
- Pathways
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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