CHI3L1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2713970

Product Details

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This CHI3L1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human CHI3L1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Cantó, Tintoré, Villar, Costa, Nurtdinov, Álvarez-Cermeño, Arrambide, Reverter, Deisenhammer, Hegen, Khademi, Olsson, Tumani, Rodríguez-Martín, Piehl, Bartos, Zimova, Kotoucova, Kuhle, Kappos et al.: "Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes. ..." in: Brain : a journal of neurology, Vol. 138, Issue Pt 4, pp. 918-31, (2015) (PubMed).

Target Details

Target: CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))

Alternative Name: Chi3l1 (CHI3L1 Products)

Synonyms: AW208766 Protein, Brp39 Protein, Gp39 Protein, ASRT7 Protein, CGP-39 Protein, GP-39 Protein, GP39 Protein, HC-gp39 Protein, HCGP-3P Protein, YKL-40 Protein, YKL40 Protein, YYL-40 Protein, hCGP-39 Protein, GP38K Protein, CLP-1 Protein, SPC-40 Protein, SPS-40 Protein, Chil1 Protein, BP40 Protein, MGP-40 Protein, chitinase-like 1 Protein, chitinase 3 like 1 Protein, chitinase 3-like 1 (cartilage glycoprotein-39) Protein, Chil1 Protein, CHI3L1 Protein, Chi3l1 Protein

Target Type: Viral Protein

Background: Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Molecular Weight: 42.4 kDa

NCBI Accession: NP_001267