ABI1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714282

Product Details

Target: ABI1 (Abl-Interactor 1 (ABI1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 4

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ABI1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ABI1 / SSH3BP1 (transcript variant 4) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ABI1 (Abl-Interactor 1 (ABI1))

Alternative Name: Abi1,ssh3bp1 (ABI1 Products)

Synonyms: ABI-1 Protein, ABLBP4 Protein, E3B1 Protein, NAP1BP Protein, SSH3BP Protein, SSH3BP1 Protein, NAP1 Protein, Ssh3bp1 Protein, E3b1 Protein, abi1 Protein, wu:fc66g09 Protein, wu:fk56a10 Protein, zgc:73174 Protein, MGC84356 Protein, ABI1 Protein, abi-1 Protein, e3b1 Protein, nap1bp Protein, ssh3bp Protein, ssh3bp1 Protein, wu:fe48a10 Protein, zgc:153534 Protein, DKFZp469P1319 Protein, abl interactor 1 Protein, abl-interactor 1 Protein, abl-interactor 1a Protein, abl interactor 1 S homeolog Protein, abl-interactor 1b Protein, Abl-interactor 1 Protein, Abl interactor 1 Protein, ABI1 Protein, Abi1 Protein, abi1a Protein, abi1.S Protein, abi1 Protein, abi1b Protein, Bm1_44660 Protein, LOAG_04356 Protein

Background: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(1011) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.

Molecular Weight: 51.7 kDa

NCBI Accession: NP_001012770

Pathways: RTK Signaling, Response to Water Deprivation, ER-Nucleus Signaling