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ACMSD Protein (Myc-DYKDDDDK Tag)

ACMSD Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714321
  • Target See all ACMSD Proteins
    ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ACMSD protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ACMSD protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ACMSD Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ACMSD (Aminocarboxymuconate Semialdehyde Decarboxylase (ACMSD))
    Alternative Name
    Acmsd (ACMSD Products)
    Synonyms
    zgc:162888 Protein, ACMSD Protein, aminocarboxymuconate semialdehyde decarboxylase Protein, aminocarboxymuconate semialdehyde decarboxylase S homeolog Protein, amino carboxymuconate semialdehyde decarboxylase Protein, ACMSD Protein, acmsd Protein, acmsd.S Protein, Acmsd Protein
    Background
    The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM, Oct 2004].
    Molecular Weight
    37.9 kDa
    NCBI Accession
    NP_612199
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