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EPS15 Protein (Myc-DYKDDDDK Tag)

EPS15 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714444
  • Target See all EPS15 Proteins
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    Protein Type
    Recombinant
    Origin
    • 1
    • 1
    Human
    Source
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This EPS15 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human AF1P / EPS15 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EPS15 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    EPS15 (Epidermal Growth Factor Receptor Pathway Substrate 15 (EPS15))
    Alternative Name
    Af1p,eps15 (EPS15 Products)
    Synonyms
    AF-1P Protein, AF1P Protein, MLLT5 Protein, CG16932 Protein, Dmel\\CG16932 Protein, EH1 Protein, EPS-15 Protein, Eps15 Protein, anon-WO0118547.85 Protein, eps-15 Protein, eps15 Protein, i31 Protein, 2410112D09Rik Protein, RGD1307641 Protein, epidermal growth factor receptor pathway substrate 15 Protein, Epidermal growth factor receptor pathway substrate clone 15 Protein, hypothetical protein Protein, EPS15 Protein, Eps-15 Protein, eps15 Protein, Eps15 Protein, PGTG_06574 Protein
    Background
    This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight
    98.5 kDa
    NCBI Accession
    NP_001972
    Pathways
    EGFR Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, EGFR Downregulation
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