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AKR1C4 Protein (Myc-DYKDDDDK Tag)

AKR1C4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2714506
  • Target See all AKR1C4 Proteins
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This AKR1C4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human AKR1C4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product AKR1C4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Alternative Name
    Akr1c4 (AKR1C4 Products)
    Synonyms
    3-alpha-HSD Protein, C11 Protein, CDR Protein, CHDR Protein, DD-4 Protein, DD4 Protein, HAKRA Protein, aldo-keto reductase family 1 member C4 Protein, AKR1C4 Protein
    Background
    This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
    Molecular Weight
    36.9 kDa
    NCBI Accession
    NP_001809
    Pathways
    Steroid Hormone Biosynthesis
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