PRKAG2 Protein (His tag)

Catalog No. ABIN2714674

Product Details

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PRKAG2 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human AMPK gamma-2 chain / PRKAG2 (full length, N-term HIS tag, transcript variant c) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRKAG2 (Protein Kinase, AMP-Activated, gamma 2 Non-Catalytic Subunit (PRKAG2))

Alternative Name: Ampk gamma-2 Chain,prkag2 (PRKAG2 Products)

Synonyms: MGC82938 Protein, PRKAG2 Protein, si:ch211-230l11.1 Protein, si:dkey-217f4.2 Protein, AAKG Protein, AAKG2 Protein, CMH6 Protein, H91620p Protein, WPWS Protein, 2410051C13Rik Protein, AI854673 Protein, protein kinase AMP-activated non-catalytic subunit gamma 2 Protein, protein kinase, AMP-activated, gamma 2 non-catalytic subunit L homeolog Protein, 5'-AMP-activated protein kinase subunit gamma-2 Protein, protein kinase, AMP-activated, gamma 2 non-catalytic subunit b Protein, protein kinase, AMP-activated, gamma 2 non-catalytic subunit Protein, Prkag2 Protein, PRKAG2 Protein, prkag2.L Protein, LOC504219 Protein, prkag2b Protein, prkag2 Protein

Background: AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 58.3 kDa

NCBI Accession: NP_001035723

Pathways: AMPK Signaling, Cellular Glucan Metabolic Process, Ribonucleoside Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Warburg Effect