AP2B1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714767

Product Details

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This AP2B1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human AP2 complex subunit beta-1 / AP2B1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: AP2B1 (Adaptor-Related Protein Complex 2, beta 1 Subunit (AP2B1))

Alternative Name: Ap2 Complex Subunit beta-1 (AP2B1 Products)

Synonyms: 5-HT(2B) Protein, 5-HT2B Protein, ADTB2 Protein, AP105B Protein, AP2-BETA Protein, CLAPB1 Protein, 1300012O03Rik Protein, AI788979 Protein, fa16e07 Protein, wu:fa16c06 Protein, wu:fa16e07 Protein, wu:fc18c08 Protein, zgc:55659 Protein, 5-hydroxytryptamine receptor 2B Protein, adaptor related protein complex 2 beta 1 subunit Protein, adaptor-related protein complex 2, beta 1 subunit Protein, adaptor related protein complex 2 beta 1 subunit L homeolog Protein, HTR2B Protein, AP2B1 Protein, Ap2b1 Protein, ap2b1 Protein, ap2b1.L Protein

Background: The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 105.5 kDa

NCBI Accession: NP_001025177

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation