Apoptosis Inhibitor 5 Protein (API5) (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all Apoptosis Inhibitor 5 (API5) Proteins
- Apoptosis Inhibitor 5 (API5)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Apoptosis Inhibitor 5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human API5 / MIG8 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product API5 Protein
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Apoptosis Inhibitor 5 (API5) (AA 400-504) protein (GST tag)
API5 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Apoptosis Inhibitor 5 (API5) (AA 2-524) protein (His tag)Crystallography grade API5 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Apoptosis Inhibitor 5 (API5) (AA 2-504) protein (His tag)Crystallography grade API5 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Apoptosis Inhibitor 5 (API5)
- Alternative Name
- Api5,mig8 (API5 Products)
- Synonyms
- AAC-11 Protein, AAC11 Protein, AI196452 Protein, api5l1 Protein, sr:nyz021 Protein, zgc:66211 Protein, wu:fb26c03 Protein, API-5B Protein, aac-11 Protein, aac11 Protein, api5 Protein, API-5A Protein, api5-A Protein, MGC83290 Protein, API5 Protein, apoptosis inhibitor 5 Protein, apoptosis inhibitor 5 S homeolog Protein, apoptosis inhibitor 5 L homeolog Protein, API5 Protein, Api5 Protein, api5 Protein, api5.S Protein, api5.L Protein
- Background
- This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Molecular Weight
- 50.6 kDa
- NCBI Accession
- NP_001136403
- Pathways
- Growth Factor Binding
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