ARHGEF7 Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2714895

Product Details

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 5

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ARHGEF7 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ARHGEF7 (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Alternative Name: Arhgef7 (ARHGEF7 Products)

Synonyms: BETA-PIX Protein, COOL-1 Protein, COOL1 Protein, Nbla10314 Protein, P50 Protein, P50BP Protein, P85 Protein, P85COOL1 Protein, P85SPR Protein, PAK3 Protein, PIXB Protein, cool1 Protein, p50 Protein, p85 Protein, pak3 Protein, pixb Protein, ARHGEF7 Protein, P85spr Protein, Pak3bp Protein, Cool Protein, PIX Protein, betaPix Protein, betaPix-b Protein, betaPix-c Protein, cool-1 Protein, mKIAA0142 Protein, p85Cool1 Protein, p85SPR Protein, arhgef7 Protein, bbh Protein, bpix Protein, im:7142367 Protein, wu:fc35h08 Protein, zgc:101775 Protein, Rho guanine nucleotide exchange factor 7 Protein, Rho guanine nucleotide exchange factor 7 S homeolog Protein, ankyrin repeat domain 10 Protein, Rho guanine nucleotide exchange factor (GEF7) Protein, Rho guanine nucleotide exchange factor (GEF) 7b Protein, ARHGEF7 Protein, arhgef7.S Protein, arhgef7 Protein, ANKRD10 Protein, Arhgef7 Protein, arhgef7b Protein

Background: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Molecular Weight: 73 kDa

NCBI Accession: NP_001106985

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation