ARNTL Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Target See all ARNTL Proteins
- ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 3
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ARNTL protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human ARNTL / BMAL1 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ARNTL Protein
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Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (AA 36-150) protein (His-IF2DI Tag)
ARNTL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (AA 1-625) protein (GST tag)ARNTL Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (AA 1-626) protein (Strep Tag)Crystallography grade ARNTL Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (AA 1-632) protein (Strep Tag)Crystallography grade ARNTL Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ARNTL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)ARNTL Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))
- Alternative Name
- Arntl,bmal1 (ARNTL Products)
- Synonyms
- BMAL1 Protein, BMAL1c Protein, JAP3 Protein, MOP3 Protein, PASD3 Protein, TIC Protein, bHLHe5 Protein, Bmal1 Protein, ARNTL Protein, xBmal1 Protein, arntl Protein, Arnt3 Protein, BMAL1b Protein, bmal1b' Protein, aryl hydrocarbon receptor nuclear translocator like Protein, aryl hydrocarbon receptor nuclear translocator-like Protein, aryl hydrocarbon receptor nuclear translocator like S homeolog Protein, ARNTL Protein, Arntl Protein, arntl.S Protein, arntl Protein
- Background
- The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 64 kDa
- NCBI Accession
- NP_001025444
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect
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