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Ataxin 3 Protein (ATXN3) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ATXN3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2715017
  • Target See all Ataxin 3 (ATXN3) Proteins
    Ataxin 3 (ATXN3)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 1
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Ataxin 3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Ataxin-3 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ATXN3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Ataxin 3 (ATXN3)
    Alternative Name
    Ataxin-3 (ATXN3 Products)
    Synonyms
    Mjd Protein, zgc:56323 Protein, ATXN3 Protein, at3 Protein, jos Protein, mjd Protein, atx3 Protein, mjd1 Protein, sca3 Protein, ataxin-3 Protein, MJD1 Protein, MGC83584 Protein, AT3 Protein, ATX3 Protein, JOS Protein, MJD Protein, SCA3 Protein, 2210008M02Rik Protein, AI463012 Protein, AI647473 Protein, Sca3 Protein, Rsca3 Protein, ataxin 3 Protein, ataxin 3 L homeolog Protein, ataxin-3 Protein, atxn3 Protein, ATXN3 Protein, atxn3.L Protein, MICPUN_104046 Protein, MICPUCDRAFT_46658 Protein, Atxn3 Protein
    Background
    Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Molecular Weight
    41.1 kDa
    NCBI Accession
    NP_004984
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