BMP3 Protein
-
- Target See all BMP3 Proteins
- BMP3 (Bone Morphogenetic Protein 3 (BMP3))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- Antibody Production (AbP), Standard (STD), Functional Studies (Func), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
-
- Recombinant human BMP3 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC-5 cells.
- Top Product
- Discover our top product BMP3 Protein
-
Bone Morphogenetic Protein 3 (BMP3) (AA 373-472) protein (GST tag)
BMP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 3 (BMP3) (AA 1-472) protein (GST tag)BMP3 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Bone Morphogenetic Protein 3 (BMP3) (AA 363-472) protein (His tag)Crystallography grade BMP3 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bone Morphogenetic Protein 3 (BMP3) (AA 359-468) protein (His tag)Crystallography grade BMP3 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Bone Morphogenetic Protein 3 (BMP3) (AA 363-472) protein (His tag)BMP3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
-
- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- BMP3 (Bone Morphogenetic Protein 3 (BMP3))
- Alternative Name
- Bmp3 (BMP3 Products)
- Synonyms
- BMP-3A Protein, PBMP3 Protein, 9130206H07 Protein, 9530029I04Rik Protein, BMP3 Protein, BMP-3 Protein, wu:fk96e01 Protein, zgc:153939 Protein, xBMP-3 Protein, bone morphogenetic protein 3 Protein, bone morphogenetic protein 3 L homeolog Protein, BMP3 Protein, Bmp3 Protein, bmp3 Protein, bmp3.L Protein
- Background
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands.
- Molecular Weight
- 13 kDa
- NCBI Accession
- NP_001192
-
