BMP7 Protein
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- Target See all BMP7 Proteins
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- CHO Cells
- Application
- Functional Studies (Func), Protein Interaction (PI), Standard (STD), Antibody Production (AbP)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human BMP7 protein expressed in CHO cells.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.02-0.04ug/mL.
- Top Product
- Discover our top product BMP7 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 0.1 % TFA
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- BMP7 (Bone Morphogenetic Protein 7 (BMP7))
- Alternative Name
- Bmp7 (BMP7 Products)
- Synonyms
- bmp-7 Protein, bmp7 Protein, op-1 Protein, BMP7 Protein, zgc:153025 Protein, OP-1 Protein, OP1 Protein, BMP-7 Protein, fb83f09 Protein, wu:fb83f09 Protein, bone morphogenetic protein 7 Protein, bone morphogenetic protein 7, gene 1 L homeolog Protein, bone morphogenetic protein 7b Protein, bone morphogenetic protein 7, gene 2 L homeolog Protein, bone morphogenetic protein 7a Protein, BMP7 Protein, bmp7.1.L Protein, LOC100136282 Protein, bmp7b Protein, Bmp7 Protein, LOC100008826 Protein, bmp7.2.L Protein, bmp7a Protein
- Background
- Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 28.8 kDa
- NCBI Accession
- NP_001710
- Pathways
- Steroid Hormone Mediated Signaling Pathway, Stem Cell Maintenance
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