HSD11B1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all HSD11B1 Proteins
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HSD11B1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human 11-beta HSD1 / HSD11B1 (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HSD11B1 Protein
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Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 196-292) protein (His-IF2DI Tag)
HSD11B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) protein (GST tag)HSD11B1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) protein (His tag)Crystallography grade HSD11B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) protein (His tag)Crystallography grade HSD11B1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 2-292) protein (rho-1D4 tag)Crystallography grade HSD11B1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 2-292) protein (rho-1D4 tag)Crystallography grade HSD11B1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) protein (His-SUMO Tag)HSD11B1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- Alternative Name
- 11-beta Hsd1,hsd11b1 (HSD11B1 Products)
- Synonyms
- 11-DH Protein, 11-beta-HSD1 Protein, CORTRD2 Protein, HDL Protein, HSD11 Protein, HSD11B Protein, HSD11L Protein, SDR26C1 Protein, hsd11 Protein, hsd11b Protein, LRRGT00065 Protein, hydroxysteroid 11-beta dehydrogenase 1 Protein, hydroxysteroid (11-beta) dehydrogenase 1b Protein, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog Protein, HSD11B1 Protein, HSD11B1b Protein, hsd11b1.L Protein, Hsd11b1 Protein
- Background
- The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
- Molecular Weight
- 32.2 kDa
- NCBI Accession
- NP_005516
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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