DDHD1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719261

Product Details

Target: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This DDHD1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human DDHD1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: DDHD1 (DDHD Domain Containing 1 (DDHD1))

Alternative Name: Ddhd1 (DDHD1 Products)

Synonyms: ddhd1 Protein, si:dkey-29m11.6 Protein, si:dkey-63j12.5 Protein, PA-PLA1 Protein, PAPLA1 Protein, SPG28 Protein, 4921528E07Rik Protein, 9630061G18Rik Protein, C85251 Protein, mKIAA1705 Protein, DDHD domain containing 1 Protein, DDHD domain containing 1b Protein, CBR-IPLA-1 protein Protein, DDHD domain containing 1 L homeolog Protein, Ddhd1 Protein, DDHD1 Protein, ddhd1b Protein, LOAG_17210 Protein, ddhd1.L Protein

Background: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 96.9 kDa

NCBI Accession: NP_085140