alpha Defensin 1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2719348

Product Details

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This alpha Defensin 1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Defensin alpha 1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

Alternative Name: Defensin alpha 1 (DEFA1 Products)

Synonyms: DEF1 Protein, DEFA2 Protein, HNP-1 Protein, HP-1 Protein, HP1 Protein, MRS Protein, Defcr Protein, Defcr1 Protein, DEFA1 Protein, Defa Protein, Def Protein, GB19392 Protein, defensin alpha 1 Protein, defensin, alpha 1 Protein, defensin alpha 5 Protein, alpha-defensin 1A Protein, defensin 1 Protein, neutrophil defensin 1 Protein, DEFA1 Protein, Defa1 Protein, Defa5 Protein, MNP1A Protein, Def1 Protein, LOC107973256 Protein

Background: Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation.

Molecular Weight: 10 kDa

NCBI Accession: NP_004075

Pathways: Cellular Response to Molecule of Bacterial Origin