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DHODH Protein (Myc-DYKDDDDK Tag)

DHODH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2719446
  • Target See all DHODH Proteins
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    Protein Type
    Recombinant
    Origin
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
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    • 1
    • 1
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    • 1
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    Human
    Source
    • 45
    • 5
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This DHODH protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human DHOdehase protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DHODH Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Sykes, Kfoury, Mercier, Wawer, Law, Haynes, Lewis, Schajnovitz, Jain, Lee, Meyer, Pierce, Tolliday, Waller, Ferrara, Eheim, Stoeckigt, Maxcy, Cobert, Bachand, Szekely, Mukherjee, Sklar, Kotz, Clish et al.: "Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. ..." in: Cell, Vol. 167, Issue 1, pp. 171-186.e15, (2016) (PubMed).

  • Target
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    Alternative Name
    Dhodehase (DHODH Products)
    Synonyms
    DHOdehase Protein, POADS Protein, URA1 Protein, 2810417D19Rik Protein, AI834883 Protein, DDBDRAFT_0167009 Protein, DDBDRAFT_0185217 Protein, DDB_0167009 Protein, DDB_0185217 Protein, DHOD Protein, DHODase Protein, XFHB_12025 Protein, dhodh Protein, dihydroorotate dehydrogenase (quinone) Protein, dihydroorotate dehydrogenase Protein, dihydroorotate dehydrogenase (quinone) L homeolog Protein, DHODH Protein, Dhodh Protein, pyrD Protein, pyr4 Protein, Mrub_0263 Protein, Arnit_2124 Protein, Trad_2703 Protein, Ftrac_1484 Protein, Ndas_0799 Protein, Mesil_1876 Protein, Slip_0841 Protein, Spirs_1436 Protein, XFHB_RS12780 Protein, dhodh.L Protein
    Background
    Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. [UniProtKB/Swiss-Prot Function]
    Molecular Weight
    41.6 kDa
    NCBI Accession
    NP_001352
    Pathways
    Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus
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