DIRAS3 Protein (Myc-DYKDDDDK Tag)
DIRAS3
Origin: Human
Host: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
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(1 reference)-
- Target See all DIRAS3 Proteins
- DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))
- Protein Type
- Recombinant
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This DIRAS3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human DIRAS3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product DIRAS3 Protein
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DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) (AA 1-229) protein (GST tag)
DIRAS3 Origin: Human Host: Wheat germ Recombinant AA, AP, ELISA, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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: "CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131833, (2015) (PubMed).
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: "CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131833, (2015) (PubMed).
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- Target
- DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))
- Alternative Name
- Diras3 (DIRAS3 Products)
- Background
- This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.
- Molecular Weight
- 25.7 kDa
- NCBI Accession
- NP_004666
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