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EIF4G1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

EIF4G1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720103
  • Target See all EIF4G1 Proteins
    EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 2
    Origin
    • 7
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This EIF4G1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human EIF4G1 / EIF4F (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EIF4G1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    EIF4G1 (Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1))
    Alternative Name
    Eif4g1,eif4f (EIF4G1 Products)
    Synonyms
    EIF4GI Protein, CG10811 Protein, Dmel\\CG10811 Protein, EIF4G Protein, Eif4G Protein, deIF4G Protein, eIF-4G Protein, eIF4g Protein, p200 Protein, EIF4G1 Protein, wu:fb50a05 Protein, wu:fc60b06 Protein, eif4g Protein, CUCUMOVIRUS MULTIPLICATION 2 Protein, CUM2 Protein, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G Protein, eukaryotic translation initiation factor 4G Protein, DDBDRAFT_0217646 Protein, DDBDRAFT_0217647 Protein, DDBDRAFT_0234257 Protein, DDB_0217646 Protein, DDB_0217647 Protein, DDB_0234257 Protein, NV18824 Protein, EIF-4G1 Protein, EIF4F Protein, P220 Protein, PARK18 Protein, p220 Protein, E030015G23Rik Protein, eIF4GI Protein, eukaryotic translation initiation factor 4 gamma 1 Protein, eukaryotic translation initiation factor 4G Protein, eukaryotic translation initiation factor 4 gamma, 1a Protein, eukaryotic translation initiation factor 4 gamma, 1 S homeolog Protein, eukaryotic initiation factor Protein, eukaryotic translation initiation factor 4 gamma Protein, eukaryotic translation initiation factor 4 gamma, 1 Protein, eukaryotic translation initiation factor 4, gamma 1 Protein, EIF4G1 Protein, eIF4G Protein, eif4g1a Protein, LOC704923 Protein, eif4g1.S Protein, EIF4G Protein, eIF4g Protein, Eif4g Protein, Eif4g1 Protein
    Background
    The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage.
    Molecular Weight
    175.3 kDa
    NCBI Accession
    NP_937884
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