EIF6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all EIF6 Proteins
- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EIF6 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human EIF6 / ITGB4BP (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product EIF6 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))
- Alternative Name
- Eif6,itgb4bp (EIF6 Products)
- Synonyms
- CAB Protein, EIF3A Protein, ITGB4BP Protein, b(2)gcn Protein, eIF-6 Protein, p27(BBP) Protein, p27BBP Protein, 1110004P11 Protein, AA408895 Protein, Itgb4bp Protein, imc-415 Protein, MGC56562 Protein, itgb4bp4 Protein, zgc:56562 Protein, wu:fc28a04 Protein, wu:ft88f05 Protein, itgb4bp Protein, eukaryotic translation initiation factor 6 Protein, Eukaryotic translation initiation factor 6 Protein, eukaryotic translation initiation factor 6 S homeolog Protein, translation initiation factor eIF6 Protein, EIF6 Protein, Eif6 Protein, eif6 Protein, eif-6 Protein, eif6.S Protein, tif6 Protein
- Background
- Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene.
- Molecular Weight
- 26.4 kDa
- NCBI Accession
- NP_852133
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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