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PI3 Protein (His tag)

PI3 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720119
  • Target See all PI3 Proteins
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Protein Type
    Recombinant
    Origin
    • 10
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PI3 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Elafin / PI3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
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    Discover our top product PI3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Buffer
    Supplied as a 0.2 μM filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
    Alternative Name
    Elafin,pi3 (PI3 Products)
    Synonyms
    ESI Protein, SKALP Protein, WAP3 Protein, WFDC14 Protein, cementoin Protein, trappin-2 Protein, TRAPPIN-2 Protein, elafin Protein, peptidase inhibitor 3 Protein, peptidase inhibitor 3, skin-derived (SKALP) Protein, PI3 Protein
    Background
    This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
    Molecular Weight
    11kD
    NCBI Accession
    NP_002629
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