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F11R Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

F11R Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2720651
  • Target See all F11R Proteins
    F11R (F11 Receptor (F11R))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 5
    Origin
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 12
    • 5
    • 4
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This F11R protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human F11 receptor (F11R), transcript variant 5 (transcript variant 5) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product F11R Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    F11R (F11 Receptor (F11R))
    Abstract
    F11R Products
    Synonyms
    CD321 Protein, JAM Protein, JAM1 Protein, JAMA Protein, JCAM Protein, KAT Protein, PAM-1 Protein, 9130004G24 Protein, AA638916 Protein, ESTM33 Protein, JAM-1 Protein, JAM-A Protein, Jcam Protein, Jcam1 Protein, Ly106 Protein, Jam1 Protein, F11 receptor Protein, F11R Protein, F11r Protein
    Background
    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5&apos alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
    Molecular Weight
    29.8 kDa
    NCBI Accession
    NP_653087
    Pathways
    Cell-Cell Junction Organization
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