FBXL18 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2720931

Product Details

Target: FBXL18 (F-Box and Leucine-Rich Repeat Protein 18 (FBXL18))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This FBXL18 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human FBXL18 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: FBXL18 (F-Box and Leucine-Rich Repeat Protein 18 (FBXL18))

Alternative Name: Fbxl18 (FBXL18 Products)

Synonyms: Fbl18 Protein, AI427077 Protein, B130019G13Rik Protein, C330021B20Rik Protein, FBXL18 Protein, zgc:114102 Protein, F-box and leucine rich repeat protein 18 Protein, F-box and leucine-rich repeat protein 18 Protein, FBXL18 Protein, Fbxl18 Protein, fbxl18 Protein

Background: The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.

Molecular Weight: 78.7 kDa

NCBI Accession: NP_079239