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FERMT3 Protein (Myc-DYKDDDDK Tag)

FERMT3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721017
  • Target See all FERMT3 Proteins
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This FERMT3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human FERMT3 (transcript variant URP2SF) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product FERMT3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    Alternative Name
    Fermt3 (FERMT3 Products)
    Synonyms
    C79673 Protein, Kindlin3 Protein, RGD1310168 Protein, MGC69069 Protein, MGC88900 Protein, KIND3 Protein, MIG-2 Protein, MIG2B Protein, UNC112C Protein, URP2 Protein, URP2SF Protein, zgc:64101 Protein, fermitin family member 3 Protein, fermitin family member 3 L homeolog Protein, fermitin family member 3b Protein, Fermt3 Protein, fermt3.L Protein, fermt3 Protein, FERMT3 Protein, fermt3b Protein
    Background
    Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molecular Weight
    75.2 kDa
    NCBI Accession
    NP_113659
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