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A2BP1 Protein (Transcript Variant 4) (Myc-DYKDDDDK Tag)

A2BP1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721335
  • Target See all A2BP1 Proteins
    A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 4
    Origin
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 3
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This A2BP1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human FOX1 / A2BP1 (transcript variant 4) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product A2BP1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
    Alternative Name
    Fox1,a2bp1 (A2BP1 Products)
    Synonyms
    A2BP1 Protein, fox1 Protein, a2bp1 Protein, zgc:103635 Protein, 2BP1 Protein, FOX-1 Protein, FOX1 Protein, HRNBP1 Protein, A2bp Protein, A2bp1 Protein, Hrnbp1 Protein, fox-1 Protein, RNA binding protein, fox-1 homolog 1 Protein, RNA binding fox-1 homolog 1 Protein, multicopper ferroxidase Protein, RNA binding protein, fox-1 homolog (C. elegans) 1 Protein, RBFOX1 Protein, rbfox1 Protein, FOX1 Protein, Rbfox1 Protein
    Background
    The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    42.6 kDa
    NCBI Accession
    NP_061193
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