GADD45GIP1 Protein (Myc-DYKDDDDK Tag)
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- Target See all GADD45GIP1 Proteins
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GADD45GIP1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GADD45GIP1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GADD45GIP1 Protein
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Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (AA 1-222) protein (GST tag)
GADD45GIP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (AA 48-222) protein (His tag)GADD45GIP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (AA 1-222) protein (Strep Tag)Crystallography grade GADD45GIP1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1) (AA 1-222) protein (Strep Tag)Crystallography grade GADD45GIP1 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, SDS, WB
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))
- Alternative Name
- Gadd45gip1 (GADD45GIP1 Products)
- Synonyms
- si:dkey-194e13.6 Protein, CKBBP2 Protein, CRIF1 Protein, PLINP Protein, PLINP-1 Protein, PRG6 Protein, Plinp1 Protein, 2310040G17Rik Protein, AI425883 Protein, Crif1 Protein, growth arrest and DNA-damage-inducible, gamma interacting protein 1 Protein, GADD45G interacting protein 1 Protein, gadd45gip1 Protein, GADD45GIP1 Protein, Gadd45gip1 Protein
- Background
- Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 25.2 kDa
- NCBI Accession
- NP_443082
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