Geminin Protein (Myc-DYKDDDDK Tag)
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- Target See all Geminin (GMNN) Proteins
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Geminin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Geminin protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GMNN Protein
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Geminin, DNA Replication Inhibitor (GMNN) (AA 110-209) protein (GST tag)
GMNN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) protein (GST tag)GMNN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Geminin, DNA Replication Inhibitor (GMNN) (AA 1-209) protein (His tag)Crystallography grade GMNN Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Geminin, DNA Replication Inhibitor (GMNN) (AA 1-206) protein (His tag)Crystallography grade GMNN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Geminin (GMNN) (Geminin, DNA Replication Inhibitor (GMNN))
- Alternative Name
- Geminin (GMNN Products)
- Synonyms
- CG3183 Protein, Dm Geminin Protein, Dm geminin Protein, Dmel\\CG3183 Protein, Gem Protein, Geminin Protein, anon-WO0257455.1 Protein, gem Protein, l(2)k14019 Protein, v(2)k09107 Protein, sb:cb254 Protein, zgc:66217 Protein, GB16871 Protein, GMNN Protein, geminin Protein, dyak_GLEANR_833 Protein, DyakGE24654 Protein, GE24654 Protein, LOC100049517 Protein, AW546347 Protein, geminin, DNA replication inhibitor Protein, CG3183 gene product from transcript CG3183-RA Protein, geminin Protein, GE24654 gene product from transcript GE24654-RA Protein, GMNN Protein, geminin Protein, gmnn Protein, LOC410093 Protein, Dyak\geminin Protein, Gmnn Protein
- Background
- This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16.
- Molecular Weight
- 23.4 kDa
- NCBI Accession
- NP_056979
- Pathways
- EGFR Signaling Pathway, DNA Replication
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