GLI1 Protein (Myc-DYKDDDDK Tag)
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- Target See all GLI1 Proteins
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GLI1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GLI1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GLI1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Alternative Name
- Gli1 (GLI1 Products)
- Synonyms
- GLI Protein, Gli Protein, Gli-1 Protein, gli1.1 Protein, AV235269 Protein, Zfp-5 Protein, Zfp5 Protein, GLI family zinc finger 1 Protein, GLI family zinc finger 1 S homeolog Protein, GLI-Kruppel family member GLI1 Protein, GLI1 Protein, Gli1 Protein, gli1.S Protein, gli1 Protein
- Background
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 117.7 kDa
- NCBI Accession
- NP_005260
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis
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