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GLI1 Protein (Myc-DYKDDDDK Tag)

GLI1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2721923
  • Target See all GLI1 Proteins
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This GLI1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human GLI1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GLI1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GLI1 (Zinc Finger Protein GLI1 (GLI1))
    Alternative Name
    Gli1 (GLI1 Products)
    Synonyms
    GLI Protein, Gli Protein, Gli-1 Protein, gli1.1 Protein, AV235269 Protein, Zfp-5 Protein, Zfp5 Protein, GLI family zinc finger 1 Protein, GLI family zinc finger 1 S homeolog Protein, GLI-Kruppel family member GLI1 Protein, GLI1 Protein, Gli1 Protein, gli1.S Protein, gli1 Protein
    Background
    This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    117.7 kDa
    NCBI Accession
    NP_005260
    Pathways
    Hedgehog Signaling, Dopaminergic Neurogenesis
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