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GSTA3 Protein (Myc-DYKDDDDK Tag)

GSTA3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2722270
  • Target See all GSTA3 Proteins
    GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
    Protein Type
    Recombinant
    Origin
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Source
    • 8
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This GSTA3 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human GSTA3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GSTA3 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
    Alternative Name
    Gsta3 (GSTA3 Products)
    Synonyms
    GSTA3 Protein, GST Protein, GSTA1 Protein, GSTA3-3 Protein, GTA3 Protein, GSTA2 Protein, Gst2-3 Protein, Yc2 Protein, glutathione S-transferase alpha 3 Protein, glutathione S-transferase A2 Protein, glutathione S-transferase Protein, glutathione S-transferase, alpha 3 Protein, glutathione S-transferase Yc Protein, GSTA3 Protein, LOC474938 Protein, gsta3 Protein, Gsta3 Protein, LOC100328911 Protein
    Background
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.
    Molecular Weight
    25.1 kDa
    NCBI Accession
    NP_000838
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