HAAO Protein (Myc-DYKDDDDK Tag)
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- Target See all HAAO Proteins
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This HAAO protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human HAAO protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product HAAO Protein
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3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (His tag)
HAAO Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (GST tag)HAAO Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 97-196) protein (GST tag)HAAO Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) protein (His tag)HAAO Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by SDS-PAGE
3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) (AA 1-286) protein (Strep Tag)Crystallography grade HAAO Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
- Alternative Name
- Haao (HAAO Products)
- Synonyms
- Afu2g17450 Protein, 0610007K21Rik Protein, 0610012J07Rik Protein, 3-HAO Protein, 3-HAOxase Protein, 3HAO Protein, zgc:103585 Protein, HAO Protein, 3-hydroxyanthranilate 3,4-dioxygenase Protein, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog Protein, SPO1774 Protein, CNB05620 Protein, AFUA_2G17450 Protein, Bcep18194_C7641 Protein, Kfla_5491 Protein, Micau_4935 Protein, RBRH_03005 Protein, Krodi_1278 Protein, haao Protein, HAAO Protein, Haao Protein, haao.L Protein
- Background
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN.
- Molecular Weight
- 32.4 kDa
- NCBI Accession
- NP_036337
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