HFE Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
Quick Overview for HFE Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722684)
Target
See all HFE ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- Transcript Variant 1
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Purification tag / Conjugate
- This HFE protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human HFE / HLAH (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Hemochromatosis (HFE) (AA 115-205) protein (GST tag)
HFE Origin: Human Host: Wheat germ Recombinant ELISA, AP, AA, WB
Hemochromatosis (HFE) proteinHFE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % pure SDS
Hemochromatosis (HFE) protein (His tag)HFE Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Hemochromatosis (HFE) (Transcript Variant 9) protein (Myc-DYKDDDDK Tag)HFE Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Hemochromatosis (HFE) (Transcript Variant 6) protein (Myc-DYKDDDDK Tag)HFE Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- HFE (Hemochromatosis (HFE))
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Alternative Name
- Hfe,hlah
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Background
- The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.
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Molecular Weight
- 37.7 kDa
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NCBI Accession
- NP_000401
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Pathways
- Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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