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IFI16 Protein (Myc-DYKDDDDK Tag)

IFI16 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2723287
  • Target See all IFI16 Proteins
    IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This IFI16 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human IFI16 / IFNGIP1 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product IFI16 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
    Alternative Name
    Ifi16,ifngip1 (IFI16 Products)
    Synonyms
    IFNGIP1 Protein, PYHIN2 Protein, IFI16 Protein, Ifitm3l Protein, Ifitml Protein, interferon gamma inducible protein 16 Protein, interferon induced transmembrane protein 2 Protein, myeloid cell nuclear differentiation antigen-like protein Protein, interferon-activable protein 203 Protein, IFI16 Protein, Ifitm2 Protein, LOC100156073 Protein, LOC488622 Protein, Ifi16 Protein
    Background
    This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    81.9 kDa
    NCBI Accession
    NP_005522
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
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