IRF4 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2723795

Product Details

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This IRF4 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human IRF4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: Irf4 (IRF4 Products)

Synonyms: LSIRF Protein, MUM1 Protein, NF-EM5 Protein, AI385587 Protein, IRF-4 Protein, Spip Protein, IRF4 Protein, si:ch73-170d1.2 Protein, irf4 Protein, interferon regulatory factor 4 Protein, interferon regulatory factor 4a Protein, Interferon regulatory factor 4 Protein, PWWP domain-containing protein MUM1 Protein, IRF4 Protein, Irf4 Protein, irf4a Protein, irf4 Protein, LOC612320 Protein, LOC100068881 Protein

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(614)(p25q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 51.6 kDa

NCBI Accession: NP_002451

Pathways: Chromatin Binding