IRF9 Protein (Myc-DYKDDDDK Tag)
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- Target See all IRF9 Proteins
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IRF9 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human IRF9 / ISGF3G protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product IRF9 Protein
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Interferon Regulatory Factor 9 (IRF9) (AA 1-220) protein (His tag)
IRF9 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Interferon Regulatory Factor 9 (IRF9) (AA 1-393) protein (GST tag)IRF9 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon Regulatory Factor 9 (IRF9) (AA 1-393) protein (Strep Tag)Crystallography grade IRF9 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Interferon Regulatory Factor 9 (IRF9) (AA 1-399) protein (Strep Tag)Crystallography grade IRF9 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- IRF9 (Interferon Regulatory Factor 9 (IRF9))
- Alternative Name
- Irf9,isgf3g (IRF9 Products)
- Synonyms
- IRF-9 Protein, ISGF3 Protein, ISGF3G Protein, p48 Protein, zgc:92097 Protein, Irf-9 Protein, Isgf3g Protein, interferon regulatory factor 9 Protein, IRF9 Protein, irf9 Protein, Irf9 Protein
- Background
- Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 43.5 kDa
- NCBI Accession
- NP_006075
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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