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KCNK4 Protein (Myc-DYKDDDDK Tag)

KCNK4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724047
  • Target See all KCNK4 Proteins
    KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))
    Protein Type
    Recombinant
    Origin
    • 2
    • 2
    Human
    Source
    • 4
    HEK-293 Cells
    Purification tag / Conjugate
    This KCNK4 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KCNK4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product KCNK4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))
    Alternative Name
    Kcnk4 (KCNK4 Products)
    Synonyms
    K2p4.1 Protein, TRAAK Protein, TRAAK1 Protein, MLZ-622 Protein, TRAAKt Protein, Tex40 Protein, KT4.1 Protein, potassium two pore domain channel subfamily K member 4 Protein, potassium channel, subfamily K, member 4 Protein, KCNK4 Protein, Kcnk4 Protein
    Background
    This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.
    Molecular Weight
    42.5 kDa
    NCBI Accession
    NP_201567
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