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Kallikrein 6 Protein (KLK6) (Transcript Variant B) (His tag)

KLK6 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2724329
  • Target See all Kallikrein 6 (KLK6) Proteins
    Kallikrein 6 (KLK6)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant B
    Origin
    • 12
    • 4
    • 3
    Human
    Source
    • 10
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Kallikrein 6 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human KLK6 / Kallikrein-6 (transcript variant B) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin Level
    < 0.1 EU per μg protein as determined by LAL test
    Top Product
    Discover our top product KLK6 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    5 mM HCl, 150 mM NaCl. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Kallikrein 6 (KLK6)
    Alternative Name
    Klk6,kallikrein-6 (KLK6 Products)
    Synonyms
    Bssp Protein, Klk7 Protein, PRSS18 Protein, PRSS9 Protein, SP59 Protein, hK6 Protein, Prss9 Protein, AI849898 Protein, BSP Protein, Klk29 Protein, MSP Protein, Prss18 Protein, neurosin Protein, kallikrein related peptidase 6 Protein, kallikrein related-peptidase 6 Protein, kallikrein-6 Protein, KLK6 Protein, Klk6 Protein, LOC100716801 Protein
    Background
    This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer&aposs and Parkinson&aposs disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
    Molecular Weight
    26.2 kDa
    NCBI Accession
    NP_001012982
    Pathways
    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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